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Celiac Disease with Dr. Ingrid of PvP Biologics, the creation of a Therapeutic for Celiac Disease, Seattle, Protein engineering, resource recommendations, and IGEM competition are all topics discussed.
Dr. Ingrid is the co-founder and the chief scientific officer of PvP Biologics, and Transnational Investigator of Institute for Protein Design
About Ingrid
“Ingrid Swanson Pultz, Ph.D., is a co-founder and the chief scientific officer of PvP Biologics. Dr. Pultz is a leader in computational enzyme design, and has a distinguished track record of leading research teams to success. As an inventor of PvP’s gluten-degrading enzyme technology and an entrepreneur, Dr. Pultz has established cross-disciplinary connections and bridged industry with academia to accomplish research goals. Dr. Pultz established PvP Biologics in 2012 and joined the team as its chief scientific officer in 2016. Prior to PvP Biologics, Dr. Pultz led the effort to develop effective therapeutics for celiac disease at the Institute for Protein Design at the University of Washington, where she held a faculty position in the Department of Biochemistry. Dr. Pultz completed her Ph.D. in microbiology at Washington in the laboratory of Dr. Samuel Miller, and post-doctoral research with Dr. David Baker. She holds a B.A. in biology from Wellesley College. While operating at the forefront of protein engineering, Dr. Pultz also has a strong interest in training the next generation of effective leaders in science and technology. Dr. Pultz has received numerous awards and recognitions including a Life Sciences Discovery Fund grant, the Neil Groman Award for Excellence in Teaching, and a competitive NSF research fellowship. ” Taken from website
About PvP Biologics
Our mission is to develop a highly-effective therapeutic product to reduce the burden of living with celiac disease. Towards this end, we are advancing a product candidate designed to break down the immuno-reactive parts of gluten in the stomach and thereby avoid the painful symptoms and damage done in the small intestine from accidental gluten ingestion.
Website https://www.pvpbio.com/
About Institute for Protein Design
“The exquisite functions of naturally occurring proteins solve the challenges faced during evolution. However, we face challenges today that were not faced during natural evolution. The goal of the Institute for Protein Design (IPD) is to develop and apply methods for designing a whole new world of synthetic proteins to address these challenges.
To achieve this goal, the Institute for Protein Design was established in 2012, and is building on strengths within the University of Washington and Seattle more generally. Protein design requires high-level expertise and talent in computing and software, biochemistry, genome sciences, biological structure, pharmacology, immunology and other basic science disciplines, as well as clinical medicine. We are marshaling deep institutional strengths in our faculty, scientific staff, postdoctoral fellows and graduate students, our partners from collaborating institutions, innovator networks, and from the computer and biotechnology industries — bringing extraordinary expertise to bear on a singular focus to advance the potential of protein design.