Immune System Rejuvenation, Startups, & Investing – Sebastian Brunemeier -Learning with Lowell 175

April 11, 2023

Sebastian Brunemeier, a biotech founder with a keen interest in the biology of aging. CEO of ImmuneAGE Pharma, focused on rejuvenating the immune system, founder of Healthspan Capital, and contributor of vitaDAO (+many more)

Over 321 books from 170 plus interviews over 5 years

https://www.learningwithlowell.com/over-321-books-from-170-interviews-over-5-years-for-autodidacts/

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PODCAST INFO:

The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.

LINKS

Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH

RSS: https://www.learningwithlowell.com/feed/podcast/

Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q

Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA

Website: https://www.learningwithlowell.com/

Links

https://www.youtube.com/channel/UCjnV3GWFhkpIiLWITq7520w

https://www.healthspancapital.vc/

https://www.linkedin.com/company/immuneage-pharma/

https://www.vitadao.com/

Timestamps / Chapters

00:00 Introduction Sebastian Brunemeier

00:15 Building in Puerto Rico

01:45 How Puerto Rico gets it’s money back

02:45 ImmuneAGE locations 

03:30 Switzerland benefits 

05:05 3rd location and distributed biotech

07:15 ChatGPT, vitaDAO, and deciding which vertices to go down

20:20 DAOs vs non profit benefits and downsides & accredited investors 

29:45 Utilizing your extra mental energy into DAOs & ageism, and hopelessness

40:10 Downhill after 18 and psychometrics 

41:50 vitaDAO, healthspan capital combination / differences

48:26 Mouse bottleneck and business opportunity 

51:00 Mouse models, synthetic models, and age related diseases

57:20 Human vs mice 

01:04:25 Cloning

01:06:45 Reverse yamanaka factors that accelerate aging, progeria cells

01:09:25 IP and investing with just a small group and contracting out, Matthew “Oki” O’Connor and Cyclarity 

01:11:50 Cylcarity, cholesterol, brain aging, and immuneAge

01:18:50 Bone marrow transplant, immuneAge special sauce 

01:30:30 Competitors that are better funded, immuneAge bone marrow transplant

01:37:50 Building a biobank of bone marrow cells / HSCs

01:42:40 Missing people on his teams

01:43:40 Keeping up to date with Sebastian Brunemeier, vitaDAO, Healthspan capital, and immuneAge

01:45:05 Books!

01:49:40 longevity biotech fellowship

01:51:30 Sebastian Brunemeier’s final words

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