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Christin Glorioso MD, Phd, & founder of NeuroAge Therapeutics and Longevity Global. Today we are digging into the drama of supplements and specifically metformin & Nir Barzilai, research into Alzheimer’s, Aubrey De Grey concerns, David Sinclair Yamanaka factor mouse studies explained, Bryan Johnson 2 million a year longevity blueprint, brain age, books, and more.
Also, special note, the waitlist for the closed beta of NeuroAge is now live. This is a rare opportunity to be on the cutting edge of science.
NeuroAge Therapeutics https://neuroagetx.com/
Christin Glorioso links
NeuroAge Therapeutics https://neuroagetx.com/
https://www.linkedin.com/in/christin-glorioso-md-phd-39627719/
drglorioso.substack.com
PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
LINKS
Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q
Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA
Linkedin: https://www.linkedin.com/in/lowell-thompson-2227b074
Twitter: https://twitter.com/LWThompson5
Website: https://www.learningwithlowell.com/
Timestamps / Chapters
00:00 Intro
01:05 Nir Brazilai, Metformin, parkinsons explained
13:20 Listener Question: 2100 what will longevity and healthspan look like for average person
16:30 Alzheimer’s research Drama explained
22:50 Alternative hypothesis for Alzhemers cause
26:12 NeuroAge deep dive, CRISPR, ML, partnerships
32:10 Biobanking, precision medicine, machine learning, yamanaka factors
37:00 Neuroage test / labspace/ 2023 goals
38:24 Hiring?
38:40 Bioinformatics, machine learning, open ai
41:25 Population size needed for neuroage test and cost/timeline
42:50 Cognition_1981 listener question / dementia regeneration potential over the next 20 years
44:44 Bryan Johnson Blueprint explained/breakdown
48:20 Genetics, personalized medicine
50:18 Diversity in test subjects
52:00 David Sinclair yamanaka factor mice study results explained
55:22 Partial vs complete reprograming (yamanaka factors)
57:15 Secrecy in biotech and CRISPR innovation
59:00 Aubrey De Grey LEV, SENS investigation, Concerns
1:03:04 Supplements, unregulated, and maybe snake oil
1:08:08 Wild west, studies, not real data (supplements)
1:09:05 Alexander hamilton liable lawsuit, history, and news concerns
1:12:06 Making supplements more safe
1:14:00 Blood donation & research empire idea
1:16:25 DrbobMaui listener question – thoughts on self decode
1:21:00 Books!
1:26:10 Longevity global events, purpose, and how to get involved