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Join Jean Hebert, a leading expert in brain health, as he delves into the transformative potential of brain tissue replacement, brain computer interfaces, and their implications for reversing aging. In this comprehensive discussion, Jean shares insights on the science of brain restoration, the challenges and innovations in the field, and the broader implications of these technologies for the future of brain health and aging. Discover how modern science is pushing the boundaries of brain health and offering hope for a future where aging can be countered.
TLDR: The key idea of the video is that brain tissue replacement has the potential to restore brain function and reverse aging, and industry partnerships could accelerate its development.
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PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
LINKS
Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH
RSS: https://www.learningwithlowell.com/feed/podcast/
Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q
Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA
Website: https://www.learningwithlowell.com/
Jean Hebert links
Timestamps / Chapters
00:00 Brain computer interfaces vs rejuvenation for brain damage
02:02 Why choose brain aging?
06:08 Specificity of tissue replacement
09:00 Rough timeline and what’s left to develop
11:20 Jean Herbert’s role at a spun out company
12:20 Startup transition / production compared to academia
14:00 Places to steal from
15:10 Amount needed to raise
16:20 Jean Hebert Thesis compared to Michael Levin to generate tissue
18:40 Neuro Cortical precursor cell types to include vs not include
21:10 Workhorse cells / Glial cells /precursor neurons
22:30 Prevent Scarring during tissue replacements
24:22 Suppressing immune system
27:05 Mice the best model for this research
30:00 AI in lab or expectations to use / FAN Q
33:13 Using surgical robots
34:00 Micro glial engineering project explained
36:40 Alzhemers / diseases for micro glial project and tissue replacement
38:00 Amyloid-beta aggregates relate to neurodegeneration FANQ
39:55 Replace the whole brain
42:30 Staging the replacement of the brain over time / process for replacement
44:30 Microrobots / microsurgery option
45:40 Mice model / adapting to intervention
48:18 Optimal time to apply the rejuvenation technology
51:40 Any other way to achieve the result hes going for outside of his approaches
54:00 Viewpoint on the role of the extracellular matrix (ECM) in the damage that needs to be addressed (FANQ)
57:30 Thermodynamic Theory of Aging (FAN Q)
59:59 Other startups being spun out of lab FANQ
01:01:00 People he is on the lookout for
01:02:24 Building in Midwest or staying in NYC
01:03:00 Book recommendations
01:03:30 how to get involved
01:05:40 Self taught people / coders/ etc finding a way to be helpful
01:07:00 Non surgical methods of tissue replacement FANq
01:09:30 Layering the cells for replacement
01:11:00 People to focus on in the aging / longevity
01:15:00 Brain in a jar
#tissuereplacement #longevity #rejuvenation