52: Stem Cell Hotel, HipSci, Imaging, Beautiful Science Images, Academia and Startups, and Advice For People Getting Started with Dr. Davide Danovi

August 28, 2018

Threading the needle between being in Academia and founding startups, fostering the next generation of innovators, building an engineer for innovation at King’s College, and amazing advice and perspective with an amazing, world class scientists, innovator, and leader.

Dr. Davide Danovi

“Dr. Davide Danovi is leading the Cell Phenotyping Unit at King’s College London in the framework of the HipSci project, funded by the Wellcome Trust and MRC.

Prior to this, he was principal scientist at Progenitor Labs, a novel biotechnology company founded to isolate drugs for regenerative medicine using innovative stem cell technologies.

Before, he worked with Prof. Austin Smith and Dr. Steve Pollard at the University of Cambridge and at University College London where he developed a live image based chemical screening platform to isolate compounds active on human neural stem cells from normal or brain tumour samples.

He holds an MD from University of Milan and a PhD in Molecular Oncology from the European Institute of Oncology where he demonstrated the causative role of the HdmX protein in human cancer.”

Director of Cell Phenotyping Platform at King’s College London

“We work in the framework of the Human Induced Pluripotent Stem Cells Initiative (HipSci) project, funded by the Wellcome Trust and MRC. We provide a dedicated laboratory space for collaborative cell phenotyping to study how intrinsic and extrinsic signals impact on human cells to develop assays for disease modeling and drug discovery and to identify new disease mechanisms.”

Director of HipSci Cell Phenotyping

“HipSci stands for Human Induced Pluripotent Stem Cell Initiative. The project brings together diverse constituents in genomics, proteomics, cell biology and clinical genetics to establish a UK national iPS cell resource (over 500 lines from patients and 500 from healthy individuals) to discover how genomic variation impacts on cellular phenotype and identify new disease mechanisms.

Strong links with NHS investigators will ensure that studies on the disease-associated cell lines will be linked to extensive clinical information. Further key features of the project are an open access model of data sharing; engagement of the wider clinical genetics community in selecting patient samples and provision of dedicated laboratory space for collaborative cell phenotyping and differentiation.”

Show notes and key links from episode with a rough estimate of when you hear them. 

 Dr. Davide’s, bio and background
~6 min mark Tim Minchin graduation
~8 min mark Stem Cell Hotel
~11 min mark Perkin Elmer Operetta CLS, one of our devices
~12 min mark The Human Induced Pluripotent Stem Cells Initiative
~14 min mark ’ The butterfly image on the HipSci twitter handle
~14 min mark Alice Vickers pattern
~15 min mark Ben Paul
~16  min mark DeepScienceVentures
~17 min mark ’ Viadynamics as an example of someone we have interacted with to mature a value proposition
~18 min mark ’Stevenage Bioscience Catalyst as an example of Open Innovation
~20 min mark Aled Edwards and the SGC as an example of Open Science towards Drug Discovery
~20 min mark when I mean ethics I mean the logistics of it, such as requirements in line with
~24 min mark this is the preprint of the publication I am referring to
~25 min mark Uri Alon and the cloud (results B can also still be result C, it’s just that the narrative pretends it linked to the hypothesis..
it is something commonly referred also as Harking, hypothesis after results are known)
(see also
and some other blogs entry
~27 min mark view from the shard (ours is really not too dissimilar, just half the height)
~30 min mark ’ Anne Carpenter review as a starting point to HCA
~30 min mark CSCRM Twitter
~32 min mark Stem Cells at Lunch and Stem Cells at Lunch digested
~32 min mark ’ Science Gallery
~32 min mark Utopia video (just presented at Bristol Science Film Festival too)
Anne Carpenter’s talk at workshop where she did a really good overview of her lab’s interest

Hyperlinked Time Stamp Show notes

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.

One comment on “52: Stem Cell Hotel, HipSci, Imaging, Beautiful Science Images, Academia and Startups, and Advice For People Getting Started with Dr. Davide Danovi

  1. Amazing and Useful article. thank you